Techniques for Diagnosis of Specimen

Techniques for Diagnosis of Specimen Question 1 Describe how your laboratory would deal with this specimen? When the liver core specimen in formalin arrive at the Histology laboratory lab, the first thing that the staff would do is the specimen accessioning, which the specimen is being accessioning y labelled it with number in order to identify each of the specimen for each of the patient (Edward C., 2013). Since the specimen arrived already been fixated with formalin in order to prevent it from decaying and also at the same time try to preserve the cells and tissues to be in a â€Å"life-like† state (Rolls Geoffey, 2011). After fixation, the next step would be grossing or known as â€Å"cut-up†, in which in this case the liver specimen need to be dissect into small pieces in order to be fit into the cassettes. After the specimens being put in the cassettes, it is then being load onto the tissue processor for processing through the wax. Tissue processors are used for preparation of paraffin section (Rolls Geoffey, 2011). It will allow the specimen to be in a molten paraffin wax state after a sequence of different solvents infiltrated in the specimen (Rolls Geoffey, 2011). Embedding is the next step where after processing, the specimen is being placed in an embedding center, placed in wax filled molds after it being removed from the cassettes (Rolls Geoffey, 2011). This is the stage where the liver specimen is being carefully oriented because in order to see the abnormal area to be visible under the microscope and thus determine the plane thoroughly (Rolls Geoffey, 2011). Using the appropriate block, the specimen is filled with wax and let it solidify for a few minutes (Rolls Geoffey, 2011). A stable base has been provided for clamping in the microtome when the cassette is now filled with wax and forming as part of the block (Rolls Geoffey, 2011). Now, section cutting process can be preceded. Section cutting is been done by using the instrument called microtome by using an extremely fine steel blade (Hubscher, S., 2008). To get only a single layer of cells that is makes up the section, the paraffin sections are usually being cut at a thickness of 3 – 5  µm (Hubscher, S., 2008). Since sectioning making it in a form of ribbons since they will stick together edge to edge making it easier to picked up onto the microscopic slides on the floated sections on the surface of warm water in a flotation bath in order to flatten them (Hubscher, S., 2008). The specimen are ready for staining after a thoroughly drying (Hubscher, S., 2008). Question 2 Which specific test could be performed within your histology laboratory to assist in the diagnosis? Why did you choose these? Based on the received liver core specimen, it shows that the total iron body content is quite high which about 20gm. Thus, the most specific test to assist in the diagnosis of the iron concentration is Perl’s Prussian blue test (PPB). Perl’s Prussian blue stain is the major histochemical stain that is used to detect as well as identified the ferric iron (Fe3+) in particular tissues [4]. By the principle of hydrolysis of mineral acid, this ferric ion then is being released from the deposition of tissues, which are protein bound. Based on chemistry’s concept itself, iron in ferric state wills formed ferric ferrocyanide since it is reacted with hydrochloric acid. Thus, this makes the insoluble blue compound visible [5]. There is no colored product by ferrous ions themselves, thus their reaction cannot be seen. Within this technique, usually red in color will represents a nuclei in that particular normal cell, yellow in color for erythrocytes, deep blue stained for ferric salts and lastly, stained as blue or black for the asbestos bodies. The stain is composed of aqueous hydrochloric acid, aqueous potassium ferrocyanide and a neutral red stain[6]. Measuring 10ml of hydrochloric acid, which is about 2% in concentration, starts the staining method. Then, 2% of potassium ferrocyanide was added and ensure that the mixture mixed thoroughly by shaking hem well. Next, placed the slides on the rack for staining step and carefully filtered the solution onto the slides and leave it with that solution for about 15 minutes. Later, carefully removed the excess solution from the slides by rinsed it using the distilled water. The step continued by filtered 1% of neutral red onto the slides and leaves it for about 5 minutes. The purposed of this step is to let the slides for having the capable time so that it will be able to attach to the dye completely [7]. About 5 minutes later, thoroughly rinsed the slides by using distilled water to remove any excess dye, which has not been attached to the cells components. The washing step should not be decreased below 5 minutes as thorough washing is required to prevent a heavy dye precipitate resulting from the neutral red counterstain [8]. The slides are then are blotted by using filter papers. Quickly, the slides were rinsed in 70% of industrial methylated spirit and at the same time agitating the slide by making a slosh up and down. Then, placed the slides in absolute industrial methylated spirit (100%) and further agitated for another one to two minutes. Finally, always placed the slides mount in a DPX-type mountant since other mounting media results in fading of the stain. Again, the slides were agitated for about 2 minutes to ensure that there was no gas trapped in the slide [9]. Then, covered the slides with cover slips by placing a mountant upon the cover-slip which is to cover the section on the slide and the slide removed from DPX and then was gently touched on the side of the slide with the section to the cover slip. Question 3 What are the expected results from the staining methods you have chosen? The pattern of iron deposition can be obtain with the help of iron staining.4 The iron stain shows the features of the possible cause of excess iron in the body. 4 The degree of the iron deposition and many grading methods exist to grade the extent of deposition in the liver by using iron stain.4 The main organs that store excess of iron is the liver. Iron stored in cell in soluble compound is called ferritin while insoluble form is called hemosiderin. Only hemosiderin that can be seen using HE stain while the ferritin cannot be seen. The hemosiderin appears as coarse golden brown refractile granules. On the Perls Prussian Blue stain, the ferritin appear as a fain bluish blush and the hemosiderin appears a deep blue in color.4 Figure 1 The liver core specimen1,2 This is the result obtain from the patient’s liver core specimen. It can be seen in the Figure 1 of large blue granules mark. This is how the presence of iron in the cell. The nuclei pigment appears red and the iron pigment appears deep blue in color with the Prussian blue stain. This means there is excess of iron stored in the liver of this patient.3 For a normal human being, excess of iron is stored in the year. Increase of the ferric iron stores can be identified as Hemochromatosis. The excess iron in body can lead to increase iron store in the liver. The iron is stored in the intracellular compartment of the liver.2 Question 4 What additional non-histological tests would you recommended to the following clinican? For the additional non-histological tests, serum ferritin blood test is recommended to be used by clinician in order to detect the content of iron in patient’s body (Adams P, 2008). It is an enzyme-linked assay that can be performed on blood sample from nonfasting patient (Adams P, 2008). 70% of the total iron store in patient’s body can be found in her haemoglobin while the 20% of the total iron stored as ferritin (Hicks R, 2013). The increase or decrease of ferritin level will indicate the changing of iron level in her body (Hicks R, 2013). The normal serum ferritin level is not more that 200ng/ML in women and normal iron level in human body is about 5 gram (Hicks R, 2013). Firstly, by referring to the Figure 2, the serum ferritin blood test will be started by drawing the blood from a vein of the patient (KidsHealth , 2014). The surface of patient’s skin will be cleaned with antiseptic and the tourniquet (elastic band) is placed around the upper arm to cause blood swell in the targeted vein (KidsHealth , 2014). Then, a needle will be inserted into the targeted vein causing the blood to withdraw from the vein and collected in a syringe (KidsHealth , 2014). When the procedure is completed, the elastic band is removed from the patient’s body part (KidsHealth , 2014). When the blood has been collected in the syringe, the needle will be removed and the targeted area will be covered with cotton in purpose to stop the bleeding (Hicks R, 2013). Question 5 Provide one provisional diagnosis for the case study and one differential diagnosis (possible alternative). A provisional diagnosis is basically the first diagnosis or the working diagnosis that is made by a medical professional and it is usually not clarify as the final diagnosis[4]. This type of diagnosis is generally assign when the presenting problems meet some of the criteria for a disorder, but more information required for the accurate diagnosis and it might be modified as the patients care continues and more details of diagnosis presented[4]. Besides, the provisional diagnosis might change depending on the patients ongoing condition, his or her response to any treatments that is offered, and also the patients level of comfort with the new diagnosis. For this case the 40-year-old post-menopausal woman presents and claimed that she had a long term lethargy, loss of sex drive, abdominal pain for 2 months and discoloration of the skin. Based on the symptoms presented the most probable provisional diagnosis for her is Hemochromatosis as the symptoms presented are quite identical (Table 1). Hemochromatosis is the most common form of iron overload disease, in this cases the total iron body content recorded was 20g, where the normal iron levels for women ranges from 12 to 15.5g of hemoglobin per deciliter of blood[2]. Primary hemochromatosis or else known as hereditary hemochromatosis, is an inherited disease meanwhile, secondary hemochromatosis is caused by anemia, alcoholism, and other disorders[1]. The Hemochromatosis causes the body to absorb and store too much iron. Apart, the extra iron builds up in the bodys organs such as liver, heart and pancreas can lead to an organ damage[1]. Table 1 Patient Presented Symptoms and Hemochromatosis Symptoms Presented Symptoms Hemochromatosis Symptoms Long term lethargy Fatigue and lack of energy[1] Loss of sex drive Loss of sexual desire[1] Abdominal pain for 2 months Abdominal pain[1] Discoloration of skin Generalized darkening of skin color (Bronzing) [1] Loss of body hair[1] There is also another type of diagnosis and it is called a differential diagnosis or possible alternative. The differential diagnosis is the process of comparison among diseases exhibiting similar sign and symptoms[3]. When a patient has symptoms that are common to more than one disease or condition, the medical professional will make a list of the possibilities, and then eliminate them based on the symptoms that may not fit some of the possibilities[3]. In this case, when evaluating a patient with suspected hemochromatosis, alcoholic liver disease and multiple transfusions should also be considered[2]. Alcoholic liver disease Liver biopsy in the alcoholic disease patients may show a modest increase in iron. In contrary to patients with hemochromatosis, the hepatic iron levels alcoholic disease patients are relatively normal and iron stores are less than 4 g[2]. Multiple transfusions Hypertransfusion is performed in patients with sickle cell anemia, beta thalassemia major and also myelodysplastic syndrome[2]. Such patients may receive as many as 100 units of red blood cells, which may contain as much as 20-25 g of iron, similar to or more than the amount retained in many symptomatic patients with hereditary hemochromatosis[2]. References Mayoclinic.org. 2014. Hemochromatosis Symptoms Diseases and Conditions Mayo Clinic. [online] Available at: http://www.mayoclinic.org/diseases- conditions/hemochromatosis/basics/symptoms/CON-20023606 [Accessed: 26 Jan 2014]. Emedicine.medscape.com. 2014. Medscape: Medscape Access. [online] Available at: http://emedicine.medscape.com/article/177216-differential [Accessed: 26 Jan 2014]. Torrey, T. 2014. differential diagnosis. [online] Available at: http://patients.about.com/od/glossary/g/diffdiagnosis.htm [Accessed: 26 Jan 2014]. Schimelpfening, N. 2014. FAQ: What Is a Provisional Diagnosis Vs. Differential Diagnosis?. [online] Available at: http://depression.about.com/od/diagnosis/f/provisional.htm [Accessed: 26 Jan 2014]. Edward C. (2013). Histotechniques. Web Path. Retrieved January 26, 2014, fromhttp://library.med.utah.edu/WebPath/HISTHTML/HISTOTCH/HISTOTCH.html Rolls Geoffey (2011). An Introduction to Specimen Preparation. Leica Biosystem. Retrieved January 26, 2014, from http://www.leicabiosystems.com/pathologyleaders/an- introduction-to-specimen-preparation/ Hubscher, S. (2008). Tissue Pathways for Liver Biopsies for the Investigation of Medical Disease and for Focal Lesions. E-med.co.il. 2014. [online] Available at: http://www.e-med.co.il/emed/new/Usersite/Presentations/Liver_Diseases/10.files/slide0014_image0 70.jpg [Accessed: 26 Jan 2014]. Library.med.utah.edu. 2014.Hepatic Pathology. [online] Available at: http://library.med.utah.edu/WebPath/LIVEHTML/LIVER018.html [Accessed: 26 Jan 2014]. Ukessays.co.uk. 2014.He stain and perls prussian blue technique. [online] Available at: http://www.ukessays.co.uk/essays/sciences/h-and-e-stain-and-perls-prussian-blue- technique.php [Accessed: 26 Jan 2014]. Rashmil, S. (n.d.). Retrieved from http://www.dako.com/index/knowledgecenter/kc_publications/kc_publications_conne ction/kc_publications_connection14.htm/28829_2010_conn14_special_stains_interpret ation_liver_biopsies_saxena.pdf Adams P (2008) Management Of Elevated Serum Ferritin Levels Journal. US National Library of Medicine, National Institute of Health (2008 May; 4(5):333-334. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720, on January 27th 2014. Hicks R (2013) Ferritin blood test. Web MD. Retrieved from http://www.webmd.boots.com/a-to-z-guides/ferritin-blood-test, on January 26th 2014. KidsHealth (2014) Blood Test: Ferritin (Iron). Retrieved from http://kidshealth.org/parent/system/medical/test_ferritin.html#, on January 25th 2014. References: [4] Liver Pathology, In-text: (Google Books, 2014), Bibliography: Google Books. 2014. Liver Pathology. [online] Available at: http://books.google.com.my/books?id=worDZk6fSWwCpg=PA289lpg=PA289dq=why+used+perls+prussian+blue+to+detect+ironsource=blots=4RfzVoc3O5sig=BBCSmpM1Cwt6xMxrNBwH8c5hvU4hl=ensa=Xei=AkDmUpLRC8SprAfC_4DYBwredir_esc=y#v=onepageq=why used perls prussian blue to detect ironf=false [Accessed: 28 Jan 2014]. [5] Perls Prossian Blue Staining Protocol, In-text: (Ihcworld.com, 2014), Bibliography: Ihcworld.com. 2014. Perls Prossian Blue Staining Protocol. [online] Available at: http://www.ihcworld.com/_protocols/special_stains/perls_prussian_blue_ellis.htm [Accessed: 28 Jan 2014]. [6] Theory and Practice of Histological Techniques, In-text: (Google Books, 2014) Bibliography: Google Books. 2014. Theory and Practice of Histological Techniques. [online] Available at: http://books.google.com.my/books?id=Dhn2KispfdQCpg=PA235lpg=PA235dq=why+Perls+prussian+blue+is+stain+with+1%+neutral+redsource=blots=JyrzjwVyH8sig=9Qlm0_6T31awaDEuhGSChtQz3mQhl=ensa=Xei=04LmUsb8POW7iAf9uYGgBwredir_esc=y#v=onepageq=why Perls prussian blue is stain with 1% neutral redf=false [Accessed: 28 Jan 2014]. [7] He stain and perls prussian blue technique, In-text: (Ukessays.co.uk, 2014) Bibliography: Ukessays.co.uk. 2014. He stain and perls prussian blue technique. [online] Available at: http://www.ukessays.co.uk/essays/sciences/h-and-e-stain-and-perls-prussian-blue-technique.php#ixzz2rcLX4KTJ [Accessed: 28 Jan 2014]. [8] Perls’ Technique For The Demonstration of Haemosiderin – Method and Tips, In-text: (skinpathonline, 2011), Bibliography: skinpathonline. 2011. Perls’ Technique For The Demonstration of Haemosiderin – Method and Tips. [online] Available at: http://skinpathonline.wordpress.com/2011/06/20/perls’-technique-for-the-demonstration-of-haemosiderin-–-method-and-tips/ [Accessed: 28 Jan 2014]. [9] Perls M. Nachweis von Eisenoxyd in gewissen Pigmenten. Virchov’ s Arch Pat Anat und Phsiol und Klin Med 1867; 39: 42-48. Van Gieson I. Laboratory notes of technical methods for the nervous sistem. New York Med J 1889; 50: 57-60. A.F.I.P.. Laboratory Methods in Histotechnology. Washington D.C. A.F.I.P. 1994. [ Accessed : 28 Jan 2014]

Design and Organisation of Management Essay

My course work is based on textile spinning that how should a manager deal with each step he makes. In textile spinning the role of a manager is totally different than in the book of management. Here the managers have to deal with everything which is possible. Director Role Designing and organizing Designing is creating the organizational structure so that work can be efficiently and effectively allocated to different departments and work units. Those work units are: > Strategy > Structure > People > Rewards > Processes In textile, there are five directors. And on those five directors the top director is the managing director. He passes the orders of what should be done and what shouldn’t be done. As being a managing director, he has four directors, working in four different departments. And these four directors tell the managing director how well the company is going on. The four directors are: > Director of Marketing > Director of Finance > Director of Operations > Director of Human Resource The director of marketing: The director of marketing is the one who market his product in the market. At first he should try to target good customers from the market who are well known or at least who will buy the product slowly but often. The director of marketing should market the product in a wide range of market where the competition is low and with good quality to maintain and gain more customers so that it would help the company grow wider. Other than this the director of marketing should find out more of the other market where his goods and services can be sold in a good price and make the company go into higher profit. The formal pattern of interactions and coordination designed by the management to link the tasks of individuals and groups in achieving organization goals. At the organisational level, dividing jobs among organizational members is called departmentation. Making departments make it easy to do work by distributing the work. As the cash going and coming would go to the accounts and finance department, selling products would go to the sales department, and handling employees and hiring new employees would go to human resource department. Distributing jobs into department make the job easy for the managing director help the company do well. And it has advantages as well. The advantages of distributing jobs are: > Efficient use of resources. > In-dept specialization and skill development. > Career progression within departments. > Excellent coordination within a function. > High quality technical problem solving. > Overall direction from top management. The disadvantages of the functional structure > Poor communication across functional departments. > Poor coordination leads to slow response to external changes. > Decision concentrated at the top of the hierarchy, creating delay. > Responsibility for problems difficult to pinpoint. > Employees have a limited view of the organisation. > Limited opportunity for development of general management skills. Producer Role Working productively The producer’s role is to work productively, adopting a productive environment, and managing stress and time. It is because, in textile if the product’s quality and quantity is low, the buyer would either returns the goods or pays the lower amount. If the quality or the quantity of cotton yarn is low than the buyer of the cotton yarn will have low profits. So the producer’s role is to maintain the quality of the product and the quantity of the product. Peak performers The producer should be: > Result oriented > Personal mission > Self management > Team mastery > Coping with change I agree with this, as in the producer should be aware of these things to satisfy the top management and the customers. Optimal performance The producer should be: > Setting goals > Being engaged > Being hypersensitive > Enjoying the experience Personal Motivation Extrinsic Motivation – these are the forces that are external to person Intrinsic motivation – these are the forces which are internal forces that are generated by the individual him or herself. They should adopt a productive environment in: > Pay and benefits > Opportunities > Job security > Pride in company > Openness/fairness > Camaraderie/friendliness This has to be given to the producer because they are the one who have a role in productivity. Otherwise they would decrease the quality and the quantity of the product. Quantity counts in textile because of the weight of the cotton yarn. And quality counts because of the strength. Pay and benefits: The pay and benefits for the producer should be given according to his know how because in this field one small mistake leads to a big one. Opportunities: The opportunities is given all the time, but mostly the cotton bales are not in good quality, so it is the producers job to make it into a good quality for the customers. Job Security: The job security should be given after the effort has been shown by the producer. Coordinator role Coordinator’s Role is: > Managing projects > Designing works > Managing across functions Coordinator role is concerned with the efficient flow of work, leading to continuity and stability. This requires the responsibility to see that the right people are at the right place at the right time to perform the right task. Coordinator should be responsible for overseeing change, lines of authority, ever changing tasks, and cross – functional activities. This competence is considered under two headings: > Project planning > Project monitoring Managing projects involves: Project monitoring: > Tracking progress. > Comparing actual results to predict. > Analysing the impact of the actual results. > Making adjustments to the plans. Coordinator should work with the project so that the project should meet the deadlines, but also the budget, the project manager is concerned with two types of information: > The amount of money budgeted for the work to be performed versus the actual cost of performing the work. > The budget cost of work performed versus the budgeted cost of work scheduled. Designing Work The coordinator should decide that whether more traditional and specialised work designs are preferred or to opt for work designs that give employees greater responsibility and greater autonomy. This decision is influenced by the technology required, the changing of the environment (in which the decision should be made quickly), and the link to the external customers. The coordinator should know the behavioural approach toward everyone. Behavioural approach should be towards the top management, middle management and the lower management. The behaviour could cost the coordinator lose his job. Job Design Strategies > Job Enlargement > Job Enrichment > Job rotation > Empowerment Job Enlargement Job enlargement is the opposite to the task of specialisation This increases the skill variety and task identity by redesigning the job to increase the number of task that the employee performs. This could be criticised because the work may not be challenging comparing to one task. This could increase the ability to complete a whole piece of work. Job Enrichment Except for increasing the variety, job enrichment increases the responsibility, decision making and feed back in the employees’ work and enhances the nature of the job relation with managers, company worker and clients. Job Rotation Job rotation helps the employees to increase their skills by allowing individuals to shift among the variety of tasks. This increases the understanding of the different jobs and their interdependencies. It can be used to reduce the boredom. Empowerment When employees are given the opportunity to inherit both thinking and doing the tasks, they will have more control over that how the work is been done, organised and controlled. This helps them to develop the ownership for the whole process, they would find the work more interesting and challenging and they will try to make the work more efficient. Monitor Role The next role we turn to is the monitor role. On the face of it this role appears less interesting than others in the competing values framework. Monitoring connotes the watchful and intrusive gaze of the bureaucrat or the snooping supervisor. Monitors sounds like people who get paid for catching others enjoying their work and putting a stop to it. Monitor may sound like controlling and nosy activity, but monitoring, in the way we describe it, is essential in maintaining high performance in both individuals and groups. The monitor function focuses the manager’s attention on the internal control issues. The monitor function is concerned with consolidating and creating continuity. These competencies are: Competency 1: Managing Information through Critical Thinking. Competency 2: Managing Information Overload. Competency 3: Managing Core Processes. To help business distinguish between activities that add value and things that do not, an expert on business strategy, purpose a model called a value chain. This value chain is a picture of all the activities a business uses to produce and deliver something its customers will value. There are five primary activities. The five primary activities involve the following: > Bringing materials or information into the organisation. > Operating on them. > Sending them out. > Marketing them. > Servicing them. The four supporting activities that surround these primary activities and help them operate more effectively are: > Firm Infrastructure. > Human Resource Management. > Technology Development. > Procurement. The Broker Role This role falls into the open systems model which is the most modern model out of them all. This role is more of an external one and involves being adaptable, innovative and flexible. All the qualities above lead to continual adoption, innovation and the ability to maintain external resources. There are three competencies associated with this role: > Building and maintaining a power base > Negotiating agreement and commitment > Presenting ideas The first competency in terms of business, power refers to the ability to make workers work and produce. They are able to exercise authority by using their power in the organization to get things done. There are four sources of power for the broker role: position power which reflects status in a company. Personal power involves personal characteristics. Expert power involves expert sing in an area and involves specializing or being skilled in a specific field. Network power is to do with the â€Å"social chapter† and information is from the people you know and trust. The second competency is negotiating agreement and commitment. They must be able to balance these qualities not only formally but also informally. Negotiation can be minor such as shift changes to discussing wages etc. Innovator Roles The innovator role focuses on adaptability and responsiveness to the external environment. It involves the use of creativity and the management changes and transition, and it provides a unique opportunity for managers to affirm the value of individual employees within the organizational setting. The meaning of the innovator means, that they tend not to think in terms of large, establishment organizations. The three key competencies of the innovator are: Competency 1: Living with Change. Competency 2: Thinking creatively. Competency 3: managing change. Each of these competencies requires the manager to be flexible and open to new ideas, new ways of thinking, and new challenges that the managerial role presents. Competency 2: Thinking creatively A very wide range of behavior and personality traits have been found to be associated with creative ability. A skill that each person can develop is a creative thinking. Creativity is was of thinking that involves the generation of new ideas and solutions. This is the process of associating known things or ideas into new combinations and relationships. People often underestimate their own creative ability. The difference between people who exhibit creative tendencies and people who don’t personal belief in creativity. Vast arrays of techniques, often called â€Å"creativity heuristics,† ranging from use of analogies to mental imagery, are available to enhance creativity skills. The major difference between creative people and others is personal belief. The individual barriers frequently have an emotional basis. The barriers result from personal beliefs and fears associated with taking risk, trying out a new idea, or trying to convince others of the value of our new ideas. Developing Creative Thinking Skills 1). Domain relevant skills: The domain relevant skill is that the more the manager knows the more creative he can be. Creative relies on linking knowledge together. 2). Creative Relevant Skills: They know how to make people to associate previously unrelated concepts and to think differently. 3). Task Motivation Creating an environment that is conductive to creativity. Competency 3: Managing Change The world is changing at a very high speed rate and so as the people and organization. And all the organizations are under pressure to change. Understanding resistance to plan change The following changes usually provoke resistance: > Changes affecting knowledge and skill needs. > Changes suggested associated with economic or status loss. > Changes suggested by others. > Changes involving risk. > Changes that disrupt social relationships. The Mentor Role The mentor role might be called the concerned human role. This role reflects a caring, empathetic orientation. In this role a manager is expected to be helpful, considerate, sensitive, approachable, open, and fair. In acting out the role, the leader listens, supports legitimate requests, conveys appreciation, and give recognitions. This competency has been shown to be a key factor that differentiates successful managers from those who have detailed. Integrity, security, and self-acceptance increase the ability to practice empathy, the key skill in helping others to grow. Empathy involves truly putting yourself in the position of others and honestly trying to see the world as they see it. References Combe, Colin, An Introduction to E-Business: Management and Strategy, 2006, Butterworth-Heinemann Ltd Abraham H. Maslow Toward a Psychology of Being, D. Van Nostrand Company, (1968) Library of Congress Catalog Card Number 68-30757 http://www.esight.org/view.cfm?x=1073 http://www.ericdigests.org/1993/esteem.htm

William Shakespeare s Venice - 1452 Words

1. In the content, Shakespeare puts a scene in Belmont against one in Venice. As specified prior Shakespeare continually compares all through The Merchant of Venice. A juxtaposition is an abstract method that makes examinations between two disparate articles. One reason that Shakespeare continually compares is for the reason that Shakespeare s deciding objective is to inspire intrigue and astound the perusers all through the story with sensational changes. To start with of act one scenes one and two, Antonio and Portia, two distinct characters are presented. An incident including Antonio in Venice and Portia in Belmont further outlines the correlation between the two. For example Antonio states, â€Å"In sooth, I know not why I am so sad†Ã¢â‚¬ ¦show more content†¦Despondently, if Antonio neglects to pay the three thousand ducats before the end of three months, then Shylock dangers to expel a pound of flesh from Antonio. At the point when Antonio is certain to the loan, th is implies Antonio is in charge of the advance and the acknowledgment of the punishment for late installment. At last, when Antonio is sure to the credit, Antonio assumes full liability for the advance. 3. In the section, Shylock speaks, â€Å"Antonio is a good man† (I.III.12). This is clarified as Shylock states, â€Å"My meaning in saying he is a good man is to have you understand me that he is sufficient† (I.III.13-14). As it were, Shylock implies that Antonio has enough cash to ensure the loan. Bassanio translates this as an undeniable proclamation this implies Skylock appreciates judging individuals and clutches feelings of spite, in the meantime, Bassanio considers this more important. For example, Bassanio states, â€Å"You shall not seal to such a bond for me! I ll rather dwell in my necessity† (I.III.150-151). This presents expect that Antonio may neglect to reimburse the advance. At last, Shylock is buoyant to accomplish revenge against Antonio whil e Bassanio considers the terms more important and stresses. 4. Shylock does a danger examination of Antonio s capacity to reimburse the advance and Shylock talks something that exceeds those dangers for Antonio. Shylock

How Shampoo Works and the Chemistry Behind It

You know shampoo cleans your hair, but do you know how it works? Here is a look at shampoo chemistry, including how shampoos work  and why its better to use shampoo than soap on your hair. What Shampoo Does Unless youve been rolling around in mud, you probably dont have hair that is truly dirty. However, it may feel greasy and look dull. Your skin produces sebum, a greasy substance, to coat and protect hair and the hair follicle. Sebum coats the cuticle or outer keratin coat of each hair strand, giving it a healthy shine. However, over time, sebum also makes your hair look dirty. An accumulation of it causes hair strands to stick together, making your locks look dull and greasy. Dust, pollen, and other particles are attracted to the sebum and stick to it. Sebum is hydrophobic. It waterproofs your skin and hair. You can rinse away salt and skin flakes, but oils and sebum are untouched by water, no matter how much you use. How Shampoo Works Shampoo contains detergent, much like you would find in dishwashing or laundry detergent or bath gel. Detergents work as surfactants. They lower the surface tension of water, making it less likely to stick to itself and more able to bind with oils and soiling particles. Part of a detergent molecule is hydrophobic. This hydrocarbon portion of the molecule binds to the sebum coating hair, as well as to any oily styling products. Detergent molecules also have a hydrophilic portion, so when you rinse your hair, the detergent is swept away by the water, carrying sebum away with it. Other Ingredients in Shampoo Conditioning Agents:  Detergents strip away the sebum from your hair, leaving the cuticle exposed and susceptible to damage. If you use soap or dishwashing detergent on your hair, it will get clean, but it may look limp, lacking body and shine. Shampoo contains ingredients that replace the protective coating on the hair. Silicones detangle hair, smooth the hair cuticle and add shine. Fatty alcohols help prevent static and fly-away or frizzy hair. Shampoo typically is more acidic than soap, so it may contain ingredients to bring down the product of the pH. If the pH of shampoo is too high, the sulfide bridges in keratin can break, weakening or damaging your hair.Protectants:  Many shampoos contain additional ingredients intended to protect hair. The most common additive is sunscreen. Other chemicals protect against heat damage from hair dryers or styling aids, chemical damage from swimming pools, or build-up from styling products.Cosmetic Ingredients:  Shampoos contain aesthetic ingredients that dont affect how well the shampoo cleans your hair but may make shampooing more pleasant or affect the color or fragrance of your hair. These additives include pearlised ingredients, which add sparkle to the product and may leave a faint glimmer on hair, perfume to scent the shampoo and hair, and colorants. Most colorants wash out with shampoo, although some subtly tint or brighten hair.Functional Ingredients:  Some ingredients are added to shampoo to keep it uniformly mixed, thicken it so that it is easier to apply, prevent the growth of bacteria and mold, and preserve it to extend its shelf life. A Word About Lather Although many shampoos contain agents to produce a lather, the bubbles dont aid the cleaning or conditioning power of the shampoo. Lathering soaps and shampoos were created because consumers enjoyed them, not because they improved the product. Similarly, getting hair squeaky clean actually isnt desirable. If your hair is clean enough to squeak, it has been stripped of its natural protective oils.